Mitochondrial diseases
Mitochondria are components of our body's cells and are responsible for producing 90% of the energy the body uses. Mitochondrial diseases usually have a genetic cause. These are often mutations in the genes that contain the blueprint of the mitochondria. They can manifest themselves through developmental disorders as well as through a range of symptoms that usually become apparent in childhood. There is a wide range of symptoms as well as severity. For example, children with the same gene mutation can be completely symptom-free, have moderate symptoms, or have a very severe outcome. The origin of these differences can only be partially explained today.
Treatment and cure
Fifteen to twenty years ago, the outlook for patients with mitochondrial disease was poor: there were no effective threrapies and no cure. There was little in the way of improvement in research. Over the past ten years, however, research has made huge advances in many areas, making the possibilities for therapies or cures for certain mitochondrial diseases tangible.
Promoting research
Research for mitochondrial disease is multidisciplinary and international. In order to develop effective therapies, a range of different competencies is required, often necessitating collaboration between different universities, laboratories and institutes. The basis for successful research is sufficient financial resources to finance the scientists, laboratory materials and instruments involved in the studies. We provide financial support to the best research teams worldwide to help in the fight against mitochondrial diseases.
From patients for patients
The Mitohelp Foundation is a non-profit foundation of patients and their families. Our mission is to give children with mitochondrial diseases a chance for therapy and cure by supporting specific research projects. We are supported by scientists and doctors who are experts in this field.
Get help with the many questions
For many patients and their families, an uncertain journey begins from the moment of diagnosis. Our experts have provided frequently asked questions and answers, and are happy to answer additional questions.